Took three kinds of antihypertensive drugs, but blood pressure is still high.

This situation is also relatively common clinically, especially in some elderly people, uremia and some other patients are more common, what should be done at this time?

1. whether the medication is correct.

Although some people eat three kinds of antihypertensive drugs, poor compliance always fails to take the medication on time, which will lead to abnormal blood pressure. Furthermore, the combination of drugs is not standardized, eat a kind of antihypertensive drugs can not add to two, and then add to three. But not all antihypertensive drugs can be combined, must be under the guidance of a professional doctor, the regular scientific combination of drugs.

For example, Priligy and Sartan are originally a large class of antihypertensive drugs, can not be used together, the conventional combination of drugs: Priligy/Sartan + diphenhydramine + diuretics, which is the most common combination of three antihypertensive drugs program, according to the heart rate can also be added to the lor antihypertensive drugs.

The need for a combination of 3 antihypertensive drugs indicates that the blood pressure is more stubborn and possibly refractory hypertension. However, these three antihypertensive drugs should include diuretics, other commonly used are long-acting calcium channel blockers, angiotensin-converting enzyme inhibitors (ACEI), or angiotensin receptor blockers (ARB), and all antihypertensive drugs are administered at the maximum tolerated dose and appropriate frequency, when the blood pressure still cannot be lowered to be considered refractory hypertension. If the antihypertensive drugs are not used in a standardized manner, or if they cannot be taken regularly on time, it does not mean that the antihypertensive program has failed.

2. the medication time is enough.

Generally, long-acting antihypertensive drugs are slow to take effect, if the combination of drugs just started, at least 2 to 4 weeks of observation time, so only the combination of drugs to achieve more than 4 weeks of blood pressure still can not come down, only then counted as program failure.

3. Exclude life factors are not well controlled

Control blood pressure, not only antihypertensive drugs, the first basis is a healthy life, some people give the task of lowering blood pressure all to antihypertensive drugs, certainly not. Because obesity, do not control the diet, stay up late, do not exercise, etc. will raise blood pressure, if you eat 3 kinds of antihypertensive drugs, blood pressure is still high, first, look at whether you stay up late, obese, do not exercise, no low-salt diet, long-term alcohol abuse and so on these factors have to be removed first.

4. Exclude drugs caused by

Some long-term use of drugs can cause blood pressure, such as oral contraceptives, cyclosporine, erythropoietin, glucocorticoids, non-steroidal anti-inflammatory drugs, antidepressants, cocaine, and certain Chinese medicines (such as licorice, ephedra), and so on. See if you have been taking these drugs for a long time.

5. the presence of factors of secondary hypertension.

In patients with refractory hypertension, about 20%-25% of them are secondary hypertension, commonly renal hypertension, renal vascular hypertension, endocrine hypertension, etc. Therefore, for patients with refractory hypertension, some screening for secondary hypertension can be carried out in conjunction with their condition.

6. Adjustment of antihypertensive drugs.

If it is indeed refractory hypertension patients, some drug adjustments can be made, such as diuretics in terms of using chlorothiazide or indapamide to replace hydrochlorothiazide, if still not up to standard can add spironolactone or eplerenone; patients with a fast heartbeat (more than 80 beats/min), can add metoprolol and other %u3B2 receptor blockers or carvedilol and other %u3B1 and %u3B2 receptor blockers, such as heartbeat is on the slow side, can add prazosin and other %u3B1 receptor blockers, can also try to use isosorbide mononitrate; for uremic patients and other patients, often need to add colistin and other central antihypertensive drugs.

7. device therapy.

For part of refractory hypertension, renal nerve ablation and some other device therapy can also achieve some good results.

Blood pressure standard is the hard truth, for patients with hypertension, only blood pressure standard, to minimize the occurrence and development of secondary cardiovascular and cerebrovascular disease caused by it. It is also said that surgery can treat refractory hypertension. The theory is that it can, but the evidence on the efficacy and safety of surgery for hypertension is still insufficient, so the method is still in the clinical research stage. In short, when you find that you are taking 3 kinds of blood pressure, and the dose is already sufficient, but your blood pressure is still high, make sure to look for a professional senior cardiovascular doctor!

4 details for taking antihypertensive drugs , otherwise the drug even if for nothing

For patients with hypertension, once the disease is developed, they need to take antihypertensive for the rest of their lives. Otherwise, the blood pressure value will rise repeatedly and the probability of inducing an acute heart attack, cerebral infarction, and other cardiovascular and cerebrovascular diseases will be very high, which will be more dangerous to health and even life. When taking medication, many precautions must be kept in mind, otherwise not only will the blood pressure value rise repeatedly, but also cause certain harm to other systems or organs.

The details for hypertensive patients to take antihypertensive drugs

1. Do not change the dose by yourself

When hypertensive patients take antihypertensive drugs, they must strictly follow the doctor's instructions to take the drug quantitatively, not to change the dose on their own.

For some hypertensive patients, after taking antihypertensive drugs for a while, the blood pressure value will always be in a stable state. So they will reduce the medication on their own, this behavior is wrong.

Once suffering from hypertension, you need to take antihypertensive drugs for life to be able to stabilize blood pressure and achieve the role of avoiding some vascular diseases.

Once you stop the medication or reduce the amount of medication on your own, it will most likely lead to unstable blood pressure, or even a sudden rise in blood pressure, which is difficult to fall.

2. Do not change your medication indiscriminately

The causes of hypertension vary, as do the degree and type of hypertension and the individual's physique.

For hypertension patients, do not choose some antihypertensive drugs to take indiscriminately, and do not mix some antihypertensive drugs.

If you change your medication frequently or take it indiscriminately, not only will it not work to lower your blood pressure, but it may also form drug resistance. Even if you take the drugs, your blood pressure will still rise.

In addition, most antihypertensive drugs can cause some harm to the kidneys.

If you take some antihypertensive drugs indiscriminately for a long time, these drugs will lead to damage to kidney function. In serious cases, it can even cause chronic kidney failure, which is very dangerous to health.

3. pay attention to life adjustment during the medication

Many hypertensive patients are taking antihypertensive drugs, still appear to drink alcohol, smoking, staying up late, as well as eating some high salt, high oil, high sugar, and other food behavior.

If hypertension patients have such behavior, it will lead to erratic blood pressure, which is very harmful to vascular health.

Therefore, hypertension patients must adjust their habits during the medication, three meals a day should be plant-based food, especially vegetables, beans, and coarse grains of food, these foods can play an auxiliary effect of lowering blood pressure.

4. Blood pressure should still be measured regularly every day

Most of the hypertension patients during  taking antihypertensive drugs, almost will not appear to monitor blood pressure, this behavior is not desirable.

For hypertensive patients, they must monitor their blood pressure every day, even if they do not feel any discomfort, they should also do a good job of monitoring their blood pressure.

It is especially important to monitor blood pressure when the temperature changes significantly.

Once the phenomenon of elevated blood pressure, accompanied by some dizziness, headache symptoms, must be quickly treated to ensure their health to the greatest extent.

All in all, hypertension patients, when taking antihypertensive drugs must pay attention to the above four points.In addition, you should take your medication regularly every day and do not miss any medication.

During the treatment period, patients should consult a doctor promptly if their blood pressure becomes unstable, and should not change their medication on their own. In addition, do not take antihypertensive drugs with drinks or milk, or other beverages.

And when taking antihypertensive drugs, you must stop smoking and drinking to stabilize blood pressure.

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The dangers of smoking for people with high blood pressure

I believe we are all very aware of the dangers of smoking. There are quite a few common diseases that have a lot to do with smoking. Even if the cause of the disease is not smoking, but after the disease, you should quit smoking before it is too late, hypertension is one of them. However, many patients do not take this seriously and still stick to the habit of smoking. This article will talk to you about smoking and hypertension, and I hope that after reading this article, people with hypertension should quit smoking in time.

Consequences of smoking for people with high blood pressure

I can tell you clearly that if a person with high blood pressure smokes, it will have a detrimental effect on his or her condition. It is a proven statement that smoking is harmful to your health, and you should quit smoking before it is too late, whether you are a hypertensive patient or not. In the case of hypertensive patients, it may continue to aggravate their condition, thus causing more serious effects.

Smoking are harmful to people with high blood pressure

• First. The effect on blood pressure levels. When the body inhales cigarettes, tar, nicotine, and other substances will enter the liver for metabolism. If you smoke for a long time, the liver is not able to metabolize the toxins completely, and then the toxins may be deposited in the blood vessels. At this time, the viscosity of the blood may increase, resulting in stagnation, causing an increase in blood pressure.

• Second. Cigarettes contain substances that may cause sympathetic, central nervous system, a certain amount of stimulation, when the body may produce catecholamines. This substance may accelerate the contraction rate of small arteries, and the blood pressure value will increase. In addition, the patient's heart contraction speed will also be accelerated, the body's blood volume may be reduced, the same will also appear to increase blood pressure.

• Thirdly. The effect of antihypertensive drugs. As we all know, after suffering from this disease, patients need to take drugs for a long time to ensure that their blood pressure is controlled within the normal range. But patients who adhere to the medication, if there is a habit of smoking, the body's sensitivity to the drug will be reduced. At this time, even if the amount of medication remains unchanged, the blood pressure will be difficult to control, and the only way to ensure that the blood pressure is worthy of stability is to increase the amount of medication.

What are the possible safety risks for people with high blood pressure who smoking?

It can be seen that patients with high blood pressure should not smoke. The impact of smoking on patients with hypertension, not only in terms of blood pressure but some safety risks will also increase, which should never be ignored, the following will take you to understand.

1, easy blood vessel blockage, increase the risk of sudden death

People suffering from hypertension, their blood vessel situation is relatively poor, and if you smoke, will only make the blood vessel situation worse. At this time, due to increased blood viscosity, there may be a risk of blood vessel blockage. If this happens in the cardiovascular system, the blood does not flow back to the heart in time, and the heart does not get enough oxygen and nutrients. If such a phenomenon is not improved for a long time, the heart function will gradually weaken, and the risk of sudden death may increase at this time.

2、Increase the risk of stroke

For patients with hypertension, their blood pressure levels rise, the pressure in the blood vessels itself is relatively large. As mentioned above, if a hypertensive patient smokes, the blood pressure value will continue to rise, so the pressure in the blood vessels will also continue to rise. At this point, our cerebral blood vessels may break down, thus causing a hemorrhagic stroke.

In addition, smoking for people with high blood pressure may also have increased blood viscosity, causing the phenomenon of blood vessel blockage, which is likely to cause an ischemic stroke if the blockage of cerebral blood vessels occurs. Many people may find that this is the same as the pathogenesis of stroke, except that patients with hypertension who smoke have a higher risk of developing the disease, so we should be cautious.

3. Increase the risk of other types of diseases

We should be clear that even if you are not a hypertensive patient, if you smoke for a long time, it will have a great impact on your health. It may lead to the prevalence of other types of diseases, typically lung diseases, cancer, etc. Cigarettes enter the body through the respiratory tract, which naturally affects lung health, and the lungs are stimulated by cigarettes for a long time, which naturally increases the risk of disease.

In addition, nicotine in cigarettes has long been classified as a carcinogen by the WHO, because it may cause cell damage, thereby increasing the risk of cellular mutations. At this time, normal cells in the body may develop into cancer cells, and when the body's immunity decreases, cancer cells may develop in a big way, thus leading to the occurrence of cancer.

Many people with hypertension, may have the habit of smoking, and usually, when they are told that they need to quit smoking, they will have various reasons to get back at you. But this is a fluke of people. By introducing you above, I hope to give you a warning to all hypertensive patients.

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